Injectable botulinum toxin formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/42 (2006.01) A61K 8/64 (2006.01) A61K 8/99 (2006.01) A61K 35/74 (2006.01) A61K 38/16 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2749757

This invention provides novel injectable compositions comprising botulinum toxin that may be administered to a subject for various therapeutic, aesthetic and/or cosmetic purposes. The injectable compositions contemplated by the invention ex-hibit one or more advantages over conventional botulinum toxin formulations, including reduced antigenicity, a reduced tendency to undergo unwanted localized diffusion following injection, increased duration of clinical efficacy or enhanced potency relative, faster onset of clinical efficacy, and/or improved stability.

La présente invention concerne de nouvelles compositions injectables comprenant la toxine botulique, lesdites compositions pouvant être administrées à un sujet dans des applications thérapeutiques, esthétiques et/ou cosmétiques variées. Les compositions injectables selon l'invention présentent un ou plusieurs avantages par rapport aux formules de toxine botulique classiques, y compris une antigénicité réduite, une tendance réduite à se diffuser localement de façon indésirable après injection, une durée d'efficacité clinique augmentée ou une puissance relative améliorée, un début plus précoce de l'effet clinique et/ou une stabilité améliorée.

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