Injectable calcium phosphate solid rods and pastes for...

Details Injectable calcium phosphate solid rods and pastes for... Injectable calcium phosphate solid rods and pastes for...

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61L 24/00 (2006.01)

Patent

CA 2537735

Osteogenic proteins are delivered via an injectable solid rod or hardenable paste. The formulation comprises a calcium phosphate material, an osteogenic protein, and optional additives and active ingredients such as a bone resorption inhibitor. Methods of making injectable pharmaceutical compositions and methods of using the osteogenic compositions to treat bone defects are also disclosed.

L'invention concerne la délivrance de protéines ostéogéniques via une barre solide ou une pâte durcissable injectable. La formulation comprend un matériau de phosphate de calcium, une protéine ostéogénique et des additifs facultatifs ainsi que des principes actifs du type inhibiteur de résorption osseuse. L'invention concerne également des procédés relatifs à l'élaboration de compositions pharmaceutiques injectables et des procédés relatifs à l'utilisation de compositions ostéogéniques pour le traitement de défectuosités osseuses.

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