Injectable collagen-based system for delivery of cells or...

A - Human Necessities – 61 – L

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Details

A61L 27/54 (2006.01) A61F 2/02 (2006.01) A61K 9/08 (2006.01) A61K 31/52 (2006.01) A61L 27/24 (2006.01) A61L 31/04 (2006.01) A61L 31/16 (2006.01) C07K 14/78 (2006.01)

Patent

CA 2361569

Disclosed herein is a method for delivering cells or a therapeutic agent to a tissue site, the method involving (a) combining the cells or therapeutic agent with a soluble collagen to form a cell-collagen or therapeutic agent-collagen solution; and (b) administering the solution to the tissue site, whereby, upon contact with the tissue, the solution is converted to a gel. Also disclosed herein are the use of this method for treating tissue defects, and useful cell- collagen and therapeutic agent-collagen solutions.

La présente invention concerne une technique permettant d'administrer des cellules ou un agent thérapeutique à un tissu. Cette technique consiste à (a) combiner les cellules ou l'agent thérapeutique avec un collagène soluble afin d'obtenir une solution cellules-collagène ou agent thérapeutique-collagène, et à (b) administrer cette solution au tissu, la solution devenant un gel après contact avec ce dernier. L'invention concerne également les utilisations de cette technique pour le traitement de défauts tissulaires, et des solutions cellules-collagène et agent thérapeutique-collagène particulièrement utiles.

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