A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/335 (2006.01) A61J 1/00 (2006.01) A61K 9/08 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01)
Patent
CA 2308082
A composition of taxol and polyethoxylated castor oil is pH balanced to have a pH less than 8.1 to improve stability. This composition can include an acid, preferably citric acid, to adjust the pH value. The invention includes a method of formulating a taxol solution for injection by mixing an acid with a carrier material, such as castor oil, to form a carrier solution after which taxol is mixed with the carrier solution to form the taxol solution at a pH of less than 8.1. The method may include the step of slurrying the taxol in alcohol before mixing with the carrier solution.
Carver David R.
Elliott Robyn
Ewald Hernita
Handreck Paul
Prout Timothy R.
Napro Biotherapeutics Inc.
Sim & Mcburney
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