Injectable implant

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01) A61K 9/00 (2006.01) A61L 27/26 (2006.01) A61L 27/54 (2006.01) A61K 47/10 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2276164

The invention concerns an in situ implant which can be made by placing by injection into an organism a sterile and water insoluble complex consisting of a biodegradable polymer and a biocompatible polyether functionalized as an end group, as well as the coagulation thereof under the action of the body fluid. The coagulate contains possibly at least one biologically active susbstance from one of the following groups: hormones, immunomodulators, immunosuppressors, antibiotics, cytostatics, diuretics, digestives, heart energizers, anti-inflammatory, analgesics, local anesthetics and/or neuropharmacological agents.

La présente invention concerne un implant in situ, pouvant être fabriqué par placement dans l'organisme d'un complexe stérile, insoluble dans l'eau et injectable, composé d'un polymère biodégradable et d'un polyéther biocompatible fonctionnalisé en groupe terminal, ainsi que sa coagulation sous l'effet du fluide biologique. Le coagulat contient éventuellement au moins une substance biologiquement active appartenant au groupe des hormones, immunomodulateurs, immunosuppresseurs, antibiotiques, cytostatiques, diurétiques, digestifs, stimulants cardiaques, anti-inflammatoires, analgésiques, anesthésiques locaux et/ou agents neuropharmacologiques.

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