Injectable liquid copolymers for soft tissue repair and...

Details Injectable liquid copolymers for soft tissue repair and... Injectable liquid copolymers for soft tissue repair and...

A - Human Necessities

61

K

A61K 31/765 (2006.01) A61L 27/18 (2006.01) C08G 63/08 (2006.01) C08G 63/64 (2006.01) C08G 63/664 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2160853

The present invention provides injectable, bioabsorbable liquid copolymers suitable for use as a soft tissue repair or augmentation material in animals comprising a liquid polymer selected from the group consisting of liquid polymers of a plurality of at least two different first lactone repeating units and liquid polymers of a plurality of first lactone and second lactone repeating units; wherein the first lactone repeating units are selected from the group consisting of ~-caprolactone repeating units, trimethylene carbonate repeating units, ether lactone repeating units (which for the purpose of this invention shall mean 1,4-dioxepan-2-one and 1,5-dioxepan-2-one) and combinations thereof and the second lactone repeating units are selected from the group consisting of glycolide repeating units, lactide repeating units (which for the purpose of this invention are defined to be L-lactide, D-lactide, or D,L-lactide repeating units), p-dioxanone repeating units and combinations thereof. Additionally, the present invention also discloses methods of using these liquid copolymers for tissue augmentation and repair as well as kits which include prefilled containers to facilitate the use of these materials.

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