A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/12 (2006.01) C12N 5/077 (2010.01) A61K 9/10 (2006.01) A61L 27/00 (2006.01) C12N 5/00 (2006.01) A61K 47/30 (2006.01)
Patent
CA 2161785
Slowly polymerizing polysaccharide hydrogels have been demonstrated to be useful as a means of delivering large numbers of isolated cells via injection. The gels promote engraftment and provide three dimensional templates for new cell growth. The resulting tissue is similar in composition and histology to naturally occurring tissue. This method can be used for a variety of reconstructive procedures, including custom molding of cell implants to reconstruct three dimensional tissue defects, as well as implantation of tissues generally. Examples demonstrate construction of muscle and cartilage tissues which are useful to repair defects such as reflux and incontinence.
Atala Anthony
Griffith-Cima Linda
Paige Keith T.
Vacanti Charles A.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Children's Medical Center Corporation
Massachusetts Institute Of Technology
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