Injectable ready-to-use solutions containing an antitumor...

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A61K 47/02 (2006.01) A61K 9/08 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) C07H 15/252 (2006.01)

Patent

CA 1291037

A B S T R A C T Injectable ready-to-use solutions containing an antitumor anthracycline glycoside. According to the invention there is provided a sterile, pyrogen-free,ready-to-use solution of an anthracycline glycoside, especially doxorubicin, which consists essen- tially of a physiologically acceptable salt of an anthra- cycline glycoside dissolved in a physiologically accepta- ble solvent therefor, which has not been reconstituted from a lyophilizate and which has a pH of from 2.5 to 6.5. The solution of the invention is particularly advantageous for the administration by injection of the anthracycline glycoside drugs, e.g. doxorubicin, in the treatment of both human and animal tumors.

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