Injectable solid hyaluronic acid carriers for delivery of...

A - Human Necessities – 61 – K

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Details

A61K 38/18 (2006.01) A61F 2/02 (2006.01) A61K 38/16 (2006.01) A61L 27/20 (2006.01) A61L 27/22 (2006.01) A61L 27/26 (2006.01) A61L 27/50 (2006.01) C07K 14/51 (2006.01)

Patent

CA 2486113

An injectable or implantable rod-shaped formulation is disclosed for delivery of osteogenic proteins. The formulation comprises hyaluronic acid derivatives and osteogenic proteins, and optional excipients and active ingredients such as a bone resorption inhibitor. Methods of making injectable rod-shaped pharmaceutical compositions and methods of using the osteogenic compositions to treat osteoporotic and/or osteopenic bone are also disclosed.

Composition injectable ou implantable sous forme de tige pour l'administration de protéine ostéogènes. Ladite composition contient des dérivés d'acide hyaluronique et des protéines ostéogènes, et éventuellement des excipients et des principes actifs tels qu'un inhibiteur de la résorption osseuse. Des procédés de préparation desdites compositions pharmaceutiques injectables en forme de tige et des procédés d'utilisation desdites compositions ostéogènes pour traiter les os ostéoporotiques et / ou ostéopéniques sont également décrits.

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