A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/114, 400/901
A61K 35/16 (2006.01) C07K 14/805 (2006.01) A61K 38/00 (2006.01) A61M 1/36 (2006.01)
Patent
CA 1054518
ABSTRACT OF THE DISCLOSURE There is provided a stroma-free hemoglobin free of plasma proteins which is obtained by washing the erythrocytes of pooled blood with a 1.6% sodium chloride solution and then again with a 0.8% sodium chloride solution, lysing the washed erythrocytes to obtain a hemolysate, filtering to remove cell stroma, adjusting the stroma-free filtered hemolysate to a pH of 7.2 to 7.4, adjusting the concentrations of calcium, mag- nesium, potassium, sodium, and chloride ions to standard blood chemistry values by the use of appropriate salts and filtering the adjusted hemolysate. The stroma-free hemoglobin free of plasma protein is useful as a plasma extender.
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