Injection formulations of avermectins and milbemycins

Details Injection formulations of avermectins and milbemycins Injection formulations of avermectins and milbemycins

A - Human Necessities

61

K

A61K 31/365 (2006.01) A61K 9/08 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2265952

The present application relates to injection formulations of avermectins and milbemycins based on a solvent mixture comprising sesame oil, medium-chain triglycerides, glycol esters or fatty acid esters and a further solvent from the group consisting of mono- or polyhydric aliphatic or aromatic alcohols and their derivatives (e.g. cyclic carbonates; acetates; acetals; ketals) or castor oil.

L'invention concerne des formulations injectables d'avermectines et de milbémycines à base d'un mélange de solvants, contenant de l'huile de sésame, des triglycérides, des glycolesters ou des esters d'acide gras à chaîne longue et un autre solvant de la série des alcools aliphatiques ou aromatiques mono- ou polyvalents et leurs dérivés (par exemple carbonates cycliques; acétates; acétals; cétals), ou bien de l'huile de ricin.

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