C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/07 (2010.01) C12N 5/079 (2010.01) A61K 35/12 (2006.01) A61L 27/26 (2006.01) A61L 27/38 (2006.01) C12N 11/08 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2495676
A three dimensional, innervated artificial tissue comprising a bio-synthetic matrix is provided. The artificial tissue supports cell growth, including surface coverage and three-dimensional cell in-growth, as well as nerve in- growth. Methods of preparing the innervated artificial tissue and methods of innervating artificial tissues or tissue substitutes are also provided. The artificial tissue is useful for in vitro testing of various pharmaceutical, cosmetic and household products.
La présente invention concerne un tissu artificiel innervé en trois dimensions comprenant une matrice biosynthétique. Ce tissu artificiel supporte la croissance cellulaire, comprenant la croissance interne de cellules en trois dimensions et à recouvrement de surface ainsi que la croissance interne de nerfs. Cette invention concerne aussi des techniques de préparation de tissu artificiel innervé et de substituts de tissu. Ce tissu artificiel convient pour des tests in vitro de divers produits pharmaceutiques, cosmétiques et ménagers.
Osler Hoskin & Harcourt Llp
Ottawa Health Research Institute
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