A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/02 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61L 12/08 (2006.01) A61P 27/04 (2006.01) A61P 27/16 (2006.01)
Patent
CA 2467764
The use of nanoparticles of inorganic materials (e.g., synthetic smectite clays) in ophthalmic and otic pharmaceutical compositions is described. The nanoparticles are utilized to modify the rheological properties of the compositions, so as to enhance the viscosity, flow characteristics, lubricity or other characteristics of the compositions. The invention is particularly directed to the provision of lubricant compositions for the eye and ear, and to enhancement of the viscosity, shear thinning and lubricity of artificial tear compositions. The figures shown demonstrate the changes in physical properties of the compositions.
L'invention concerne l'utilisation de nanoparticules de matériaux inorganiques (par exemple, argiles smectiques synthétiques) dans des compositions pharmaceutiques ophtalmiques et otiques. Ces nanoparticules servent à modifier les propriétés rhéologiques des compositions, de façon à modifier la viscosité, le régime d'écoulement, le pouvoir lubrifiant ou d'autres caractéristiques desdites compositions. L'invention concerne notamment la fabrication de compositions lubrifiantes pour les yeux et les oreilles ainsi que le renforcement de la viscosité, de la fluidification et du pouvoir lubrifiant des larmes artificielles.
Ketelson Howard Allen
Meadows David L.
Alcon Inc.
Smart & Biggar
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