A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/00 (2006.01)
Patent
CA 2322199
The present invention provides for the use in the manufacture of a topical medicament for the in vivo potentiation of the immune system during a viral skin infection resultant from virus replication in the epidermis, of a topical formulation comprising a source of nitrogen oxides, characterized in that the source of nitrogen oxides is produced when a pharmaceutically acceptable acidifying agent and a pharmaceutically acceptable donor of nitrogen oxides or a precursor therefor are brought into intimate contact at a site of biological action. The invention also provides delivery systems for the topical medicament.
La présente invention concerne une formulation à usage local destinée à la fabrication d'un médicament à usage local permettant de stimuler le système immunitaire in vivo lors d'une infection virale cutanée provoquée par la reproduction d'un virus sur l'épiderme. Ladite formulation à usage local comprend une source d'oxydes d'azote, caractérisée en ce qu'elle est formée par la mise en contact étroit, sur un site d'action biologique, d'un agent acidifiant pharmaceutiquement acceptable et d'un donneur d'oxydes d'azote pharmaceutiquement acceptable ou d'un précurseur de celui-ci. L'invention concerne également des systèmes d'administration du médicament à usage local.
Benjamin Nigel
Ormerod Anthony
Aberdeen University
Adams Thomas
LandOfFree
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