Inorganic selenium for treatment of benign tumors

Details Inorganic selenium for treatment of benign tumors Inorganic selenium for treatment of benign tumors

A - Human Necessities

61

K

A61K 33/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2644445

The invention relates to the use of selenate or its pharmaceutically acceptable salts, in nutritional or supranutritional amounts, in methods and compositions for inhibiting the growth of benign tumor cells and treating or preventing benign tumors, particularly benign tumors in which the Akt signaling pathway is activated or in which Bcl 2 levels are elevated. Methods of preventing malignant conversion of benign tumors and benign tumor cells to malignant tumors or malignant tumor cells is also described.

L'invention concerne du sélénate ou ses sels pharmaceutiquement acceptables, en quantités nutritionnelles ou supra nutritionnelles, utilisé dans des procédés et des compositions d'inhibition de la croissance de cellules tumorales bénines et de traitement ou de prévention de tumeurs bénines, en particulier de tumeurs bénines dans lesquelles la voie de signalisation Akt est activée ou dans lesquelles les concentrations de Bcl 2 sont élevées. L'invention concerne également des procédés permettant d'empêcher la transformation maligne de tumeurs bénines et de cellules tumorales bénines en tumeurs malignes ou en cellules tumorales malignes.

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