Inosine/guanosine derivatives

C - Chemistry – Metallurgy – 07 – H

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C07H 19/04 (2006.01) A61K 31/10 (2006.01) C07H 19/052 (2006.01) C07H 19/056 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2027023

This invention relates to novel compounds of the formula Image wherein X1 and X2 are each independently hydrogen or halogen with the proviso that at least one of X1 and X2 is a halogen atom, A1 and A2 are each independently hydrogen, halogen or hydroxy with the provisos that where A1 is hydroxy, A2 is hydrogen, and where A2 is hydroxy, A1 is hydrogen, Y1 is nitrogen, a CH group, a CCl group, a CBr group or a CNH2 group, Y2 is nitrogen or a CH group, and Z is hydrogen, halogen, or NH2, which are useful as antiprotozoal agents.

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