A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/662 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07F 9/28 (2006.01)
Patent
CA 2542967
Phosphorus substituted mycophenolate derivatives with anti-cancer, anti-viral, anti-inflammatory and anti-tissue/organ transplant rejection properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit tumor growth, viral growth, inflammation, and tissue/organ transplant rejection and/or are useful therapeutically for the treatment or prevention of cancer, viral infection, inflammation and tissue/organ transplant rejection, as well as in assays for the detection of cancer, viral infection, inflammation and tissue/organ transplant rejection.
L'invention porte sur des dérivés de mycophénolate à substitution phosphore aux propriétés anticancer, antivirales, anti-inflammatoires et anti-rejet des transplants de tissus et d'organes, et sont utilisables à des fins thérapeutiques et autres. Ces compositions inhibent la croissance des tumeurs, la croissance des virus, les inflammations et le rejet des transplants de tissus et d'organes et/ou présentent des utilisations dans le traitement du cancer, des infections virales, des inflammations et du rejet des transplants de tissus et d'organes ainsi que dans des essais de détection du cancer, des infections virales, des inflammations et du rejet des transplants de tissus et d'organes.
Cho Aesop
Chong Lee S.
Fardis Maria
Kirschberg Thorsten A.
Watkins Will
Gilead Sciences Inc.
Robic
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