Inositol derivatives for inhibiting superoxide anion production

Details Inositol derivatives for inhibiting superoxide anion production Inositol derivatives for inhibiting superoxide anion production

C - Chemistry, Metallurgy

07

F

C07F 9/117 (2006.01) A61K 31/6615 (2006.01) A61K 45/06 (2006.01) A61P 39/06 (2006.01)

Patent

CA 2361066

Inositol derivatives, compositions comprising inositol derivatives, and methods for using the compositions comprising inositol derivatives as agents for inhibiting superoxide anion production are described. The inositol derivatives are obtainable via conventional organic synthesis. The inositol derivatives inhibit superoxide anion produced by neutrophils and macrophages which cause tissue damage, see figure 1.

L'invention concerne des dérivés d'inositol, des compositions renfermant lesdits dérivés, ainsi que des méthodes d'utilisation de ces compositions renfermant des dérivés d'inositol comme agents d'inhibition de la production d'anions superoxyde. Ces dérivés d'inositol s'obtiennent par synthèse organique classique. Ils inhibent les anions superoxyde produits par les neutrophiles et les macrophages responsables de la dégradation des tissus (voir figure).

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