Inositol phosphoglycan derivatives and their medical uses

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 3/04 (2006.01) A61K 31/70 (2006.01) C07H 3/06 (2006.01) C07H 5/06 (2006.01) C07H 15/207 (2006.01)

Patent

CA 2433857

Compounds having a mimetic or antagonistic property of an inositol phosphoglycan, and the uses of these compounds are disclosed, together with the use, e.g. to treat a condition ameliorated by administration of an IPG second messenger or an IPG antagonist thereof. Preferred compounds of the invention are based on the substituted cyclitols, and in particular, the compounds are based on the linkage of two or more sugar residues to a cyclitol.

L'invention concerne des composés possédant une propriété mimétique ou antagoniste d'un phosphoglycane d'inositol, et les utilisations de ces composés, par exemple pour traiter un état pathologique amélioré par l'administration d'un second messager IPG ou d'un antagoniste IPG de celui-ci. Les composés préférés de l'invention sont basés sur les cyclitols substitués et, en particulier, sur la liaison de deux ou de plusieurs résidus de sucre à un cyclitol.

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