Inositol pyrophosphates, and methods of use thereof

Details Inositol pyrophosphates, and methods of use thereof Inositol pyrophosphates, and methods of use thereof

A - Human Necessities

61

K

A61K 31/66 (2006.01) A61K 31/70 (2006.01) A61K 31/715 (2006.01) C07F 9/02 (2006.01) C07F 9/117 (2006.01) C07F 9/6574 (2006.01) C07H 15/207 (2006.01)

Patent

CA 2488230

The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphosphate (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells.

Composés, compositions contenant ces composés et méthodes qui permettent la fourniture d'inositol hexaphosphate (IHP) modifié comportant un noyau interne au cytoplasme de cellules de mammifères. Dans certains modes de réalisation, la présente invention concerne des composés, des compositions contenant ces composés et des méthodes qui améliorent la capacité des globules rouges de mammifères à apporter de l'oxygène, lesdites méthodes consistant à fournir du IHP au cytoplasme des globules rouges.

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