Inositolglycans having insulin-like action

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 11/00 (2006.01) A61K 31/70 (2006.01) A61K 38/28 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01) C07H 3/04 (2006.01) C07H 3/06 (2006.01) C07H 13/00 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2222103

Inositolglycans having insulin-like action Compounds of the formula I A-Z-R (I) are described, where A is the radical H - P(O)(OH) -, H - P(S)(OH) -, HO-- P(S)(OH) -, HS-P(S)(OH) -, (C1-C4) - alkyl - P(O)(OH) -, (C1-C4) - alkyl - P(S)(OH)-, S(O)2(OR1) -, S(O)(OR1)-, NH2 - C(O) -, R1R2N -, R1R2N - C(O) - NH -, R1O - SO2 - NH -, (C1-C4) - alkyl - SO2 -, (C1-C4) - alkyl - S(O) - or R1 - S -, Z is 2 to 6 substituted or unsubstituted sugar radicals and R is substituted or unsubstituted inositol. The compounds of the formula I are suitable for the treatment of diabetes mellitus or noninsulin-dependent diabetes.

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