C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/327.3, 260/5
C07C 49/753 (2006.01) C07C 45/29 (2006.01) C07C 45/65 (2006.01) C07C 45/67 (2006.01) C07C 49/255 (2006.01) C07C 49/517 (2006.01) C07C 215/44 (2006.01) C07D 309/12 (2006.01) C07D 339/08 (2006.01)
Patent
CA 1293259
Abstract of the Disclosure Disclosed is a novel inosose compound represented by the general formula: Image wherein X1 and X2 are both halogen; X1 is hydrogen and X2 is halogen; or X1 is -SQ1 and X2 is -SQ2 (each of Q1 and Q2 is lower alkyl or Q1 and Q2 may form lower alkylene), R1 is a protective group for hydroxyl and Y is =O, =N-Z (Z is hydroxyl which may be protected) or Image (A is hydrogen or an amine residue), particularly to the compound wherein the symbol Y is oxygen. The inosose compound is useful as intermediates for production of valiolamine and the N-substituted derivatives thereof, which have potent .alpha.-glucosidase inhibiting activities and are useful as preventives or therapeutics for symptoms of hyperglycemia and various diseases derived therefrom in human and animals, such as diabetes, obesity and hyperlipemia.
546261
Fukase Hiroshi
Horii Satoshi
Fetherstonhaugh & Co.
Takeda Pharmaceutical Company Limited
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