Insect ammunition vectors and methods of use to identify...

Details Insect ammunition vectors and methods of use to identify... Insect ammunition vectors and methods of use to identify...

G - Physics

01

N

G01N 33/00 (2006.01) A01K 67/00 (2006.01) A01K 67/033 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2443736

The present invention provides methods for identifying pesticide targets and pesticidal agents using transposable elements in insects and insect cells lines. The invention provides engineered transposable elements for use in identification of pesticide targets. The invention further provides a biological array, a collection of transgenic insect lines or insect cell lines, the genome of each containing at least one transposable element that mutates one of the insect's genes, such that the complete collection contains a mutation in essentially every gene in the insect's genome.

La présente invention concerne des méthodes qui servent à identifier des cibles de pesticides et des produits pesticides au moyen d'éléments transposables chez un insecte ou dans des lignées cellulaires d'insectes. L'invention concerne des éléments transposables pouvant être utilisés pour l'identification de cibles de pesticides. Elle concerne en outre un jeu ordonné d'échantillons biologiques, un ensemble de lignées d'insectes transgéniques ou de lignées cellulaires d'insectes dont chacune présente un génome contenant au moins un élément transposable qui opère une mutation dans un gène de l'insecte, si bien que tout l'ensemble contient une mutation dans pratiquement chaque gène du génome.

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