Insecticidal agents

A - Human Necessities – 01 – N

Patent

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Details

A01N 63/00 (2006.01) A01N 37/46 (2006.01) A01N 63/02 (2006.01) C07K 14/24 (2006.01) C12N 1/20 (2006.01) C12N 15/63 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2351611

Disclosed are novel strains of Xenorhabdus bovienii deposited with NCIMB under accession numbers NCIMB 40985 and NCIMB 40986 which are a source of orally acting pesticides. Also disclosed are pesticidal agents which are (i) obtainable from a X. bovienii strains; (ii) have oral insecticidal activity against one or more species of insect of the order Lepidoptera, Coleoptera or Homoptera; (iii) are substantially heat stable to 50 ~C; and (iv) act synergistically with B. thuringiensis cells as an oral insecticide. The invention further makes available nucleic acids encoding these and variant toxins, plus vectors, host cells and plants transformed with the same. Also disclosed are insecticidal polypeptides (and antibodies raised to them) and compositions, plus methods of using all of these materials for the control of pests, particularly insects.

Cette invention se rapporte à de nouvelles souches de Xenorhabdus bovienii déposées auprès de NCIMB sous les numéros d'entrée NCIMB 40985 et NCIMB 40986 et qui constituent une source de pesticides à action orale. Cette invention concerne également des agents pesticides: (i) qui peuvent être obtenus à partir de souches de X. bovienii; (ii) qui ont une activité insecticide contre une ou plusieurs espèces d'insectes de l'ordre des lepidoptères, des coléoptères ou des homoptères; (iii) qui sont thermiquement stables jusqu'à 50 ·C; et (iv) qui agissent en synergie avec des cellules de B. thuringiensis en tant qu'insecticide oral. Cette invention rend en outre disponible des acides nucléiques codant ces agents et des toxines variantes, ainsi que des vecteurs, des cellules hôtes et des plantes transfomés par ces agents. Cette invention concerne également des polypeptides insecticides (et des anticorps dressés contre eux) ainsi que des compositions et des procédés d'utilisation de toutes ces substances dans la lutte contre les parasites, notamment les insectes.

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