Insecticidal protein toxins from photorhabdus

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/31 (2006.01) A01H 5/00 (2006.01) A01N 63/00 (2006.01) A01N 63/02 (2006.01) C07K 14/195 (2006.01) C07K 14/24 (2006.01) C12N 1/20 (2006.01) C12N 9/52 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2209659

Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.

L'invention porte sur des protéines issues de l'espèce bactérienne Photorhabdus et toxiques pour les insectes exposés à celles-ci. Photorhabdus luminescens (ex-Xenorhabdus luminescens), qui a été découvert dans des échantillons cliniques de mammifères, s'est révélé comme étant un symbiote bactérien de nématodes entomopathogènes de l'espèce Heterorhabditis. Il est possible d'appliquer ces toxines protéiques sur de la nourriture pour larves d'insecte ou des plantes leur convenant ou bien de les produire par génie génétique dans ces aliments ou ces plantes et ce, aux fins de la lutte contre les insectes.

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