Insecticidal toxins derived from funnel web (atrax or...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A01H 5/00 (2006.01) A01N 43/50 (2006.01) A01N 63/00 (2006.01) A01N 63/02 (2006.01) A61K 47/48 (2006.01) C07K 14/435 (2006.01) C12N 7/01 (2006.01)

Patent

CA 2128421

The invention relates to toxins from venom of Australian funnel web spider species. Eight toxins are specifically exemplifi- ed. The toxins have a molecular weight approx 4000 amu, containing 36-37 amino acids and are capable of forming 3 intrachain disulphide bridges. Polynucleotides which encode the toxins, insect viruses and plants which express the toxins and variants of the toxins are also included.

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