Insulating polynucleotides derived from element d4z4 and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/63 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2695106

Polynucleotides with insulating properties allowing protection of the expression of a transgene from adjacent cis elements in higher eukaryotic cells. In particular, these polynucleotides can be used for transgenesis, gene therapy and the production of recombinant proteins.

L'invention porte sur des polynucléotides présentant des propriétés isolantes permettant la protection de l'expression d'un transgène à partir d'éléments cis adjacents dans des cellules eucaryotes supérieures. En particulier, ces polynucléotides peuvent être utilisés pour la transgenèse, la thérapie génique et la production de protéines recombinantes.

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