Insulin analogue

Details Insulin analogue Insulin analogue

C - Chemistry, Metallurgy

07

K

C07K 14/62 (2006.01) A61K 38/17 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2334859

A novel analogue of insulin has covalently conjugated thereto, preferably at the B1 residue, 3,3',5'-triiodothyroxine. The conjugate is believed to be hepatoselective, whilst it retains insulin receptor binding properties.

On décrit un nouvel analogue de l'insuline dans lequel un 3,3',5'-tri-iodothyroxine est conjugué par covalence, de préférence au niveau du résidu B1. Le conjugué est estimé être hépatosélectif pendant qu'il conserve des propriétés de liaison au récepteur de l'insuline.

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