Insulin and igf-1 receptor agonists and antagonists

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 14/65 (2006.01) A61K 38/04 (2006.01) A61K 38/28 (2006.01) A61K 38/30 (2006.01) A61P 3/10 (2006.01) C07K 7/00 (2006.01) C07K 14/62 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2460055

Peptide sequences capable of binding to insulin and/or insulin-like growth factor receptors with either agonist or antagonist activity and identified from various peptide libraries are disclosed. This invention also identifies at least two different binding sites, which are present on insulin and insulin- like growth factor receptors, and which selectively bind the peptides of this invention. As agonists, certain of the peptides of this invention may be useful for development as therapeutics to supplement or replace endogenous peptide hormones. The antagonists may also be developed as therapeutics.

L'invention concerne des séquences de peptides capables de se fixer à des récepteurs de l'insuline et/ou du facteur insulinoïde avec une activité soit agoniste soit antagoniste et identifiés à partir de diverses banques de peptides. Cette invention identifie également au moins deux sites de fixation différents présents sur des récepteurs de l'insuline et du facteur insulinoïde, lesquels fixent sélectivement les peptides de cette invention. En tant qu'agonistes, certains des peptides de cette invention peuvent être utiles à un développement en tant que thérapeutiques pour venir en renfort des hormones peptidiques endogènes ou les remplacer. Les antagonistes peuvent aussi être développés en tant que thérapeutiques.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Insulin and igf-1 receptor agonists and antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Insulin and igf-1 receptor agonists and antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Insulin and igf-1 receptor agonists and antagonists will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1856657

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.