Insulin-associated peptides with effects on cerebral health

Details Insulin-associated peptides with effects on cerebral health Insulin-associated peptides with effects on cerebral health

A - Human Necessities

61

K

A61K 38/28 (2006.01) C07K 14/62 (2006.01)

Patent

CA 2485217

The present invention provides compositions and methods for ameliorating neurological, attention, or memory disorders and improving learning and cognition through the delivery of insulin A-chain and analogs thereof to subject. Insulin A-chain, peptides comprising the 21 amino acid sequence GIVEQ CCASV CSLYQ LENYC N (SEQ ID NO:1), and functional analogs thereof are disclosed to modulate neurological activity when administered to a subject. The methods of the invention can be used to prevent or treat neurological disorders as well as improve memory retention and acquisition. The invention includes pharmaceutical compositions comprising a therapeutically or prophylactically effective amount of insulin A-chain peptide or a functional analogs thereof.

L'invention concerne des compositions et des méthodes destinées à atténuer les troubles neurologiques, les troubles de l'attention ou les troubles de la mémoire, et à améliorer l'apprentissage et la cognition par l'administration à un sujet d'une chaîne A d'insuline et de ses analogues. L'invention concerne également une chaîne A d'insuline, des peptides comprenant la séquence de 21 acides aminés GIVEQ CCASV CSLYQ LENYC N (SEQ ID NO:1), ainsi que des analogues fonctionnels desdits peptides, destinés à moduler l'activité neurologique par administration à un sujet. Les méthodes selon l'invention peuvent être utilisées pour prévenir ou traiter les troubles neurologiques, et pour améliorer l'acquisition et la fixation mnémoniques. L'invention concerne encore des compositions pharmaceutiques contenant une quantité efficace du point de vue thérapeutique ou prophylactique de peptide d'insuline de chaîne A ou d'analogues fonctionnels de celui-ci.

Affiliated with

Also associated with

Rating

Insulin-associated peptides with effects on cerebral health does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Insulin-associated peptides with effects on cerebral health, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Insulin-associated peptides with effects on cerebral health will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1420330