Insulin compounds

Details Insulin compounds Insulin compounds

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) A61K 38/28 (2006.01) C07K 14/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2049961

2049961 9011299 PCTABS00002 Novel insulin compounds having a desirably protracted insulin action and/or antigenicity are provided. The novel insulin compounds are represented by formula (II), wherein E individually represents Glu or a neutral amino acid residue which can be coded for by nucleotide sequences, N represents an amino acid residue which can be coded for by nucleotide sequences, T represents Thr or Arg, X represents Thr, Ser, Ala or OH, and Y represents OR or NR1R2, where R, R1 and R2 individually represents hydrogen or lower alkyl, but is not present when X represents OH.

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