Insulin derivatives modified in the b 30 position, processes...

Details Insulin derivatives modified in the b 30 position, processes... Insulin derivatives modified in the b 30 position, processes...

C - Chemistry, Metallurgy

07

K

195/128.2, 530/7

C07K 14/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1247545

Abstract of the disclosure: The invention relates to insulin derivatives of the formula I Image (I) in which R1 denotes H or H-Phe, R30 reprsents the radical of a neutral, genetically codable L-aminoacid whose OH group, where present, can be free or protected by a physiologically acceptable group, and R31 denotes a physiologically acceptable neutral group SN blocking the carboxyl group, processes for their preparation and their use, and pharmaceutical agents for the treatment of diabetes mellitus.

463810

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