Insulin derivatives, processes for their preparation and...

C - Chemistry – Metallurgy – 07 – K

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530/7.4, 167/103

C07K 14/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1246548

Abstract of the disclosure: The invention relates to insulin derivatives of the formula I Image (I) in which R1 denotes H or H-Phe, R30 represents the radical of a neutral L-aminoacid and R31 represents a physiologically acceptable organic group of basic character with up to 50 carbon atoms, these derivatives having an isoelectric point between 5.8 and 8.5, processes for their prepar- ation and their use, and agents containing these derivatives for the treatment of diabetes mellitus.

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