Insulin-like growth factor agonist peptides

Details Insulin-like growth factor agonist peptides Insulin-like growth factor agonist peptides

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 38/30 (2006.01) C07K 7/00 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2286264

Compounds are provided that inhibit the interaction of an IGF with any (one) of its binding proteins but do not bind to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.

L'invention porte sur des composés inhibant l'interaction du facteur de croissance de l'insuline (IGF) avec toutes ses protéines de fixation, mais ne se fixant pas au récepteur humain de l'IGF. Ces composés agonistes de l'IGF, qui incluent des peptides, s'avèrent utiles pour accroître les niveaux d'IGF dans le sérum et les tissus des mammifères.

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