C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/65 (2006.01) A61K 38/30 (2006.01) A61P 5/02 (2006.01)
Patent
CA 2356257
IGF-I and insulin variants are provided that selectively bind to IGFBP-1 or IGFBP-3. These agonist variants are useful, for example, to improve the half- lives of IGF-I and insulin, respectively.
On décrit des variants de IGF-1 et d'insuline qui se lient sélectivement à IGFBP-1 ou IGFBP-3. Ces variants d'agoniste sont utiles par exemple pour améliorer les demi-vies de IGF-1 et de l'insuline respectivement.
Dubaquie Yves
Lowman Henry
Genentech Inc.
Smart & Biggar
LandOfFree
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