A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/28 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01)
Patent
CA 2441260
The invention relates to a pharmaceutical formulation containing: a polypeptide selected from a group containing insulin, an insulin metabolite, an insulin analog, an insulin derivative or combinations thereof; a surfactant or combinations of several surfactants; optionally, a preservative or combinations of several preservatives, and; optionally, an isotonizing agent, buffers or additional adjuvants or combinations thereof, whereby the pharmaceutical formulation does not contain any zinc or only a small quantity of zinc. The invention also relates to the production of insulin preparations of the aforementioned type.
L'invention concerne une formulation pharmaceutique contenant un polypeptide sélectionné dans un groupe comprenant : l'insuline, un métabolite d'insuline, un analogon d'insuline, un dérivé d'insuline ou une combinaison desdits constituants ; un tensioactif ou des combinaisons de plusieurs tensioactifs, éventuellement un agent conservateur ou des combinaisons de plusieurs agents conservateurs et éventuellement un agent d'isotonisation, des tampons ou d'autres additifs ou des combinaisons desdits constituants. La formulation pharmaceutique est exempte de zinc ou à faible teneur en zinc. L'invention concerne en outre la production de telles préparations d'insuline.
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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