Insulin producing cell-line obtained by electrofusion

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/07 (2006.01) A61K 35/39 (2006.01) A61K 38/28 (2006.01) A61K 48/00 (2006.01) C12N 5/16 (2006.01) C12N 5/22 (2006.01) C12P 21/02 (2006.01) C07K 14/62 (2006.01) C12M 1/42 (2006.01)

Patent

CA 2418072

The invention provides insulin secreting human pancreatic cell lines and a process for their production from the electrofusion of normal human islet cells with immortal human cell lines to generate hybrid fusion cells which are able to produce insulin. The invention also provides uses for cell-lines.

La présente invention concerne des lignées cellulaires pancréatiques humaines sécrétrices d'insuline et un procédé de production de ces dernières à partir de l'électrofusion de cellules sécrétrices d'insuline humaines normales et de lignées cellulaires humaines immortelles, destiné à produire des cellules de fusion hybrides capables de sécréter de l'insuline. L'invention se rapporte également à des utilisations des lignées cellulaires précitées.

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