Integral analytical element

G - Physics – 01 – N

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150/1

G01N 31/22 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1069419

INTEGRAL ANALYTICAL ELEMENT Abstract of the Disclosure There is disclosed an analytical element for the detection of an agent under analysis, termed analyte, dis- solved in an aqueous, proteinaceous liquid. The element has at least two superposed layers, the layers including a spreading layer and a reagent layer. The element can in- clude a support material which is preferably radiation transmissive. To normalize transport of the analyte in and through the spreading layer, the spreading layer contains an effective amount of a surfactant, such as a non ionic sur- factant. Preferably, the amount of surfactant is between about 1% and about 15% by weight of solid contents in the spreading layer. -1-

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