Integral solid gel-lattice dosage form of high moisture content

Details Integral solid gel-lattice dosage form of high moisture content Integral solid gel-lattice dosage form of high moisture content

A - Human Necessities

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A61K 9/00 (2006.01) A23L 1/05 (2006.01) A61K 9/20 (2006.01) B01J 13/02 (2006.01)

Patent

CA 1041905

ABSTRACT OF THE DISCLOSURE Integral, solid dosage forms containing active chemical compounds in a high moisture content macromolecular gel-lattice vehicle. The gel-lattice matrix vehicle may contain various active chemical compounds in the form of aqueous solutions, aqueous colloidal suspensions, aqueous macro- and microcrystalline suspensions. The gel-lattice matrix vehicle comprises from 4-50% water and sets to a relatively rigid, but not brittle, gel system upon cooling and drying to a final water content of 5-20%, typically 15-20%. The gel-lattice matrix dosageform is sufficiently stable that no capsule covering or shell is required. The gel-lattice dosage forms are extruded or die-formed in various shapes, and do not stick together in bulk. The dosage forms may be used as carriers for various types of chemical compounds, including pharmaceuticals, medicinals, foods, and cosmetics.

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