Integrated circuit hydrated sensor apparatus with electronic...

G - Physics – 01 – N

Patent

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G01N 27/26 (2006.01) A61B 5/00 (2006.01) A61B 5/15 (2006.01) A61M 3/00 (2006.01) G01N 33/487 (2006.01)

Patent

CA 2072311

- 119 - ABSTRACT OF THE INVENTION A plastic covered nonconducting substrate with an electrical circuit means is secured to the extent to withstand the presence of liquids in contact with the substrate. The covered substrate can have the substrate with one or more fluid preconditionable electrical components, a housing secured to the substrate to maintain contact of the preconditioning fluid with the electrical component like a sensor, and moisture impervious seals to cover openings in the housing for the disposition of the preconditioning fluid in the housing for contact with the electrical component on the substrate. The housing can have one or more parts and have one or more channels for containing the preconditioning fluid. The substrate with electrical components can be with a sensor assembly generally and have an improved electronic wiring board having a thermistor and at least one sensor supported, in close relation, one to the other, on one side of the board and a heater supported on the other side of the board to provide heat in response to temperature sensed by the thermistor, to at least the region where the thermistor and the sensor are positioned on the board to control the temperature of the region of the board within a narrow distribution of temperatures. The sensor assembly with or without the improved wiring board can be used in a single use disposable fluid sample collector, sensing, and calibration device. This device contains a collector like a syringe, with one or more analyte sensors, and a calibrator for calibrating the sensor. These can be pre-assembled; the analyte sensor may be connected to a self-contained monitoring instrument or analyzer which processes the signals from the sensor and displays the information to the operator. Also the sensor assembly can be used in a portable, ready-for-use analyte measuring device for the measurement of multiple - 120 - sequential fluid samples. The device has a disposable cartridge, a calibrating fluid external to the cartridge and an analyzer. The cartridge has a housing, inlet for introduction of fluids into the housing, sensor element in fluid connection with the inlet, at least one unidirectional valve in fluid connection with the sensor element, and a waste collection area or reservoir in fluid connection to the valve. The sensor apparatus alone or in the single use or multiple use mode can be sealed in a hermetically sealed layer that is impervious to gas and moisture and is a diffusion-tight boundary or barrier and that contains at least one preconditioning fluid. The preconditioning fluid is an activating fluid when the sensor is in an unsealed housing and can be either or both the activating fluid or a controlled-content fluid when the sensor is in a sealed housing.

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