A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A01N 63/00 (2006.01) C12N 15/85 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2362476
The present invention is directed to methods of repairing dystrophic, differentiated neural tissue, such as a damaged or diseased retina or optic nerve, in humans and other animals. In particular, the invention relates to introduction of adult-derived neural progenitor cells into a dystrophic neural tissue site of an animal recipient, including an adult (mature) animal, whether xenogeneic, allogeneic, or syngeneic. These adult-derived, neural progenitor cells can functionally and morphologically integrate into both mature and immature, dystrophic neural tissue.
La présente invention concerne des méthodes de réparation des tissus nerveux différenciés dystrophiques, tels qu'une rétine endommagée ou malade ou un nerf optique endommagé ou malade, chez l'homme et autres animaux. L'invention concerne, en particulier, l'introduction de cellules progénitrices neurales dérivées de l'adulte au niveau d'un site tissulaire neural dystrophique d'un animal destinataire, y compris un animal adulte (mature), qu'il soit xénogénique, allogénique ou syngénique. Ces cellules progénitrices neurales dérivées de l'adulte peuvent s'intégrer fonctionnellement et morphologiquement dans les tissus nerveux dystrophiques matures et immatures.
Gage Fred H.
Klassen Henry
Ray Jasodhara
Whiteley Simon J.
Young Michael J.
Ridout & Maybee Llp
The Salk Institute For Biological Studies
The Schepens Eye Research Institute Inc.
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