Integrin receptor antagonists

Details Integrin receptor antagonists Integrin receptor antagonists

A - Human Necessities

61

K

A61K 31/55 (2006.01) C07D 223/16 (2006.01) C07D 243/14 (2006.01) C07D 267/14 (2006.01) C07D 281/10 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2298544

Compounds of the formula (I) are disclosed which are dual fibrinogen receptor and vitronectin receptor antagonists and are useful in the treatment of atherosclerosis, in the prevention of restenosis and in the prevention of tumor metastasis and tumor growth.

L'invention concerne des composés selon la formule (I). Ces composés sont des antagonistes du récepteur de la vitronectine et du récepteur du fibrinogène. Ces composés permettent de traiter l'athérosclérose, de prévenir la resténose et de prévenir également les métastases tumorales et la croissance tumorale.

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