Integrin-targeting vectors having transfection activity

Details Integrin-targeting vectors having transfection activity Integrin-targeting vectors having transfection activity

C - Chemistry, Metallurgy

12

N

C12N 15/88 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2288840

A complex that comprises (i) a nucleic acid, (ii) an integrin-binding component, for example, an intergrin-binding peptide, (iii) a polycationic nucleic acid-binding component, for example, oligolysine, and (iv) a lipid component, for example, a cationic liposome, has transfection activity.

Complexe composé (i) d'un acide nucléique, (ii) d'un constituant de fixation à intégrine, par exemple, un peptide de fixation à intégrine, (iii) d'un constituant polycationique de fixation à l'acide nucléique, par exemple, oligolysine, et (iv) d'un constituant lipidique, par exemple, un liposome cationique. Ce complexe présente une activité de transfection.

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