Inter-alpha-trypsin as a marker for sepsis

Details Inter-alpha-trypsin as a marker for sepsis Inter-alpha-trypsin as a marker for sepsis

G - Physics

01

N

G01N 33/53 (2006.01) C12Q 1/37 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2401647

The invention provides a method of diagnosing sepsis in a mammal by contacting a bodily fluid from the mammal with a ligand which binds to an inter-alpha trypsin inhibitor (ITI) polypeptide under conditions sufficient to form an ITI- ligand complex and detecting the complex.

L'invention porte sur une méthode de diagnostic des sepsies chez les mammifères, par mise en contact d'un de leurs fluides corporels avec un ligand qui se fixe à un polypeptide inhibiteur de l'inter-alpha trypsine (ITI) dans des conditions suffisantes pour former un complexe ITI-ligand, puis détection du complexe.

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