A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 12/14 (2006.01)
Patent
CA 2718444
Methods of inhibiting the uptake of cationic biocides into medical devices such as contact lenses and im-plants are described. Methods of stabi-lizing emulsions containing cationic bio-cides are also described. In particular, the present invention provides for the use of polymers acting as labile anionic polyelectrolytes to reversibly bind cationic biocides. The reversible binding can reduce the deleterious effects of cationic biocides while maintaining bio-cidal activity. Preferred polymers in-clude galactomannan and polyvinyl alco-hol.
La présente invention concerne des procédés dinhibition de labsorption de biocides cationiques dans des dispositifs médicaux tels que des lentilles de contact et des implants. La présente invention concerne en outre des procédés de stabilisation démulsions contenant des biocides cationiques. En particulier, la présente invention concerne lutilisation de polymères agissant en tant que polyélectrolytes anioniques labiles pour lier de manière réversible des biocides cationiques. La liaison réversible peut réduire les effets délétères de biocides cationiques tout en maintenant lactivité biocide. Les polymères préférés comprennent le galactomannane et lalcool polyvinylique.
Dassanayake Nissanke L.
Desousa Ryan
Ketelson Howard Allen
Luck Mary E.
Alcon Research Ltd.
Smart & Biggar
LandOfFree
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