Interaction of cyclin d1 and estrogen receptor and its use...

Details Interaction of cyclin d1 and estrogen receptor and its use... Interaction of cyclin d1 and estrogen receptor and its use...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2249396

The present invention relates to the finding that cyclin D1 interacts with the estrogen receptor to provide activation of estrogen responsive genes. The present invention provides in vitro and in vivo assays to measure the interaction. The in vivo assays may be conducted in cells which grow in response to estrogen, particularly breast tumour cells.

Selon la présente invention, on a découvert que la cycline (D1) a une interaction avec le récepteur d'oestrogène et assure l'activation des gènes sensibles à l'oestrogène. La présente invention concerne des dosages in vitro et in vivo permettant de mesurer cette interaction. Les dosages in vivo peuvent être effectués dans des cellules qui prolifèrent en réponse à l'oestrogène, notamment dans les cellules tumorales du sein.

Affiliated with

Also associated with

Rating

Interaction of cyclin d1 and estrogen receptor and its use... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Interaction of cyclin d1 and estrogen receptor and its use..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Interaction of cyclin d1 and estrogen receptor and its use... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1596168