Intercellular adhesion molecules and their binding ligands

Details Intercellular adhesion molecules and their binding ligands Intercellular adhesion molecules and their binding ligands

C - Chemistry, Metallurgy

12

N

167/129, 167/139

C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07K 1/22 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 5/12 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/567 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341399

The present invention relates to intercellular adhesion molecules (ICAM-1) which are involved in the process through which lymphocytes recognize and migrate to sites of inflammation as well as attach to cellular substrates during inflammation. The invention is directed toward such molecules, screening assays for identifying such molecules and antibodies capable of binding such molecules. The invention also includes uses for adhesion molecules and for the antibodies that are capable of binding them.

565749

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