Intercellular adhesion molecules and their binding ligands

Details Intercellular adhesion molecules and their binding ligands Intercellular adhesion molecules and their binding ligands

C - Chemistry, Metallurgy

07

K

167/129, 530/13,

C07K 14/435 (2006.01) A61K 38/00 (2006.01) A61K 38/13 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/12 (2006.01) G01N 33/574 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1341185

The present invention relates to intercellular adhesion molecules such as ICAM-1 which are involved in the process through which populations of lymphocytes recognize and adhere to cellular substrates so that they may migrate to sites of inflammation and interact with cells during inflammatory reactions. The present invention additionally relates to ligand molecules capable of binding to such intercellular adhesion molecules, to a screening assay for these ligands, and to uses for the intercellular adhesion molecule, the ligand molecules, and the screening assay.

613303

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