Interfacial biomaterials

Details Interfacial biomaterials Interfacial biomaterials

C - Chemistry, Metallurgy

07

K

C07K 7/04 (2006.01) A61K 47/42 (2006.01) A61L 27/22 (2006.01) A61L 27/34 (2006.01) C07K 1/00 (2006.01) C07K 5/04 (2006.01) C07K 17/00 (2006.01) C07K 17/08 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2467836

An interfacial biomaterial prepared using a plurality of binding agents, each binding agent including a first ligand that specifically binds a non~biological substrate and a second ligand that specifically binds a biological substrate. Also provided is an interfacial biomaterial prepared using a plurality of binding agents, each binding agent including a ligand that specifically binds a non-biological substrate and a non-binding domain that shows substantially no binding to a biological substrate. Also provided are methods for preparing a binding agent, methods for preparing an interfacial biomaterial, and methods for using interfacial biomaterials.

L'invention concerne un biomatériau interfacial préparé à partir d'une pluralité d'agents liants, chaque agent liant renfermant un premier ligand qui se fixe de manière spécifique sur un substrat non biologique et un second ligand qui se fixe de manière spécifique sur un substrat biologique. L'invention concerne également un biomatériau interfacial préparé à partir d'une pluralité d'agents liants, chaque agent liant renfermant un ligand qui se fixe de manière spécifique sur un substrat non biologique et un domaine non liant qui ne se fixe pas ou quasiment pas sur un substrat biologique. L'invention concerne également des méthodes servant à la préparation d'un agent liant, des méthodes servant à la préparation d'un biomatériau interfacial, ainsi que des méthodes servant à l'utilisation de biomatériaux interfaciaux.

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