Interfering rnas targeting the morbillivirus nucleoprotein gene

Details Interfering rnas targeting the morbillivirus nucleoprotein gene Interfering rnas targeting the morbillivirus nucleoprotein gene

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/7105 (2006.01) A61K 31/713 (2006.01) A61K 48/00 (2006.01) A61P 31/14 (2006.01) C07H 21/02 (2006.01) C12N 15/45 (2006.01)

Patent

CA 2634334

The invention relates to interfering RNAs (siRNAs, shRNAs or pre-miRNAs) directed against conserved regions of the mRNA of the N gene encoding the morbillivirus nucleoprotein. The invention also relates to the use of said interfering RNAs for the production of medicaments for use in the treatment or prevention of a morbillivirus infection.

L'invention est relative à des ARN interférents (siARN, shARN ou pré-miARN) dirigés contre des régions conservées de l'ARNm du gène N codant pour la nucléoprotéine de morbillivirus. L'invention est également relative à l'utilisation desdits ARN interférents pour l'obtention de médicaments destinés au traitement ou à la prévention d'une infection à morbillivirus.

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